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Monoclonal Anti-Ubiquitinated histone H2B antibody

Yeda Research & Development Co., Ltd
posted on 08/10/2011

A novel antibody which can be used, for the first time, to recognize ubiquitinated histone 2B. This technology is novel in its ability to recognize proteins and their destinations, and may serve in diagnostics and immunoprecipitation processes.

Suggested Uses

Primary applications in research. Use as a detection tool in western blotting, immunoprecipitation and chromatin immunoprecipitation. Might be used for monitoring processes associated with modulations of ubiquitinated-H2B levels.

Innovation Details

Detailed Description

The invention involves the generation of antibodies specific to ubiquitinated-H2B which selectively recognize H2B when it is ubiquitinated but not H2B in its unmodified state, or ubiquitin unconjugated to H2B.

File Number: 1397 

IP Protection

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This innovation currently is not available for online licensing. Please contact Shiraz Kalir at Yeda Research & Development Co., Ltd for more information.

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Principal Investigator:

Moshe Oren Moshe Oren

Innovations (2)

Case Manager:

Shiraz Kalir Shiraz Kalir

Innovations (56)

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February 11, 2009

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