GABAa Receptor alpha2 Knockin Mice

University of Pittsburgh
posted on 03/13/2012

This is a transgenic animal available for licensing.

Innovation Details

Detailed Description

Knock-in mice were constructed with mutations in the α2 (H(270), A(277)) subunits of the GABAA receptor, which resulted in receptors that lacked modulation by ethanol but retained normal responses to GABA in vitro.

Neurosci Lett. 2011 Jan 13;488(1):31-5.

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File Number: 2259 

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