Transgenic Mice for Testing and Screening Anti-Fibrotic Therapy

University of California System: University of California, San Diego
posted on 06/15/2011

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UC San Diego investigators have created transgenic mice that could be useful as an animal model for any type of fibrosis study. Their advantage is that any individual mouse could be assayed at any point in time without sacrificing the mouse. Also, any type of collagen Type I fibrosis could be studied in these mice, including cardiovascular, pulmonary, kidney, or cystic fibrosis. While not a high throughput system, the mice could be a secondary screening for therapeutic agents for anti-fibrotic drugs.

File Number: 21775 

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