Autism

"Autism is a general term used to describe a group of complex developmental brain disorders known as Pervasive Developmental Disorders (PDD). The other pervasive developmental disorders are PDD-NOS (Pervasive Developmental Disorder – Not Otherwise Specified), Asperger's Syndrome, Rett Syndrome and Childhood Disintegrative Disorder. Many parents and professionals refer to this group as Autism Spectrum Disorders." - Autism Speaks

The Latest Innovations

Emory 13 AUG 10	Biomarkers for presymptomatic screening and diagnosing of ASD Applications A useful tool to screen and diagnose presymptomatic and asymptomatic populations with ASD based on DNA methylation patterns. Feasibility to develop into a routine test for new born screening in the long run. Highlights Employs non-invasive sample collection...
Harvard University OTD 30 JUL 10	Novel Target for Angelman Syndrome and Autism Spectrum Disorders MARKETS ADDRESSED : Angelman syndrome (AS) and Autistic spectrum disorders ( ASD ): Although it has been known for more than a decade that mutation of Ube3A results in AS, remarkably little is understood about the role of Ube3A in the cognitive impairment underlying AS. This lack of insight h...
Harvard University OTD 09 JUL 10	Portfolio of Novel Monoamine Uptake Inhibitors Targeting Monoamine Transporters MARKETS ADDRESSED : Monoamine transporters are principal targets of widely used therapeutic agents to treat depression, attention deficit hyperactivity disorder, narcolepsy, obsessive-compulsive disorders, anxiety disorders, nicotine addiction, autism and others. Compounds of this class are a...
UCSD TTO 06 MAY 10	Novel Therapeutic Approach for the Treatment of Autism Spectrum Disorders The neuroligins are a family of postsynaptic transmembrane proteins that associate with presynaptic partners, the beta-neurexins. Neurexins and neuroligins play a critical role in initiating formation and differentiation of synaptic junctions. A certain mutation in a neuroligin has been identifi...
UCSD TTO 02 APR 10	New Early Diagnostic Test for Autism Brief description unavailable
Emory 24 MAR 10	Abelson Helper Integration Site 1 (Ahi1) Rabbit Polyclonal Antibody Applications Immunoblotting Immunoprecipitation Immunocytochemistry Immunohistochemistry Specificity Mouse Ahi1 isoforms Subtype Rabbit Polyclonal Technical Summary A number of neurological disorders are associated with genes that regulate neurogenesis and neural...
Columbia Tech Ventures 19 MAR 10	Identifying Copy Number Alterations in High Throughput Sequencing of Captured Genomic Material Lead Inventors: Raul Rabadan, Ph.D. ; Vladimir Trifonov, Ph.D. Problem or Unmet Need: The genome is enriched for duplications that vary extensively in copy number. Variation in the copy number has been associated with recurrent g...
Harvard University OTD 06 MAR 10	Brainbow mice: A technicolor approach to map the neuronal circuits MARKETS ADDRESSED : This invention is a set of fluorescent protein transgenic mice whose neurons have the potential to display every color of the rainbow. In these mice, various neuronal cell types possess multiple fluorescent protein sequences uniquely flanked with pairs of incompatible Lox ...
Columbia Tech Ventures 25 JAN 10	Using Brain Activity Patterns to Indicate Specific Diagnostic Categories Lead Inventor: Joy Hirsch Ph.D. Problem or Unmet Need: Functional magnetic resonance imaging (fMRI) has been established as a common technology to locate specific cortical areas active ...
Vanderbilt 25 JAN 10	Use of Dexatromethorphan; Sodium Benzoate, Phenylacetate and Phenylbuterate to Treat Autism Associated with Increased Levels of Glutamine and Glycine. -
See All 32 innovations

People

	Trude Amick University of North Carolina at Chapel Hill Innovations (18)
	Tech Transfer Columbia Technology Ventures Innovations (913)
	Christine Najdowski Wisconsin Alumni Research Foundation (University of Wisconsin) Innovations (845)
	Michael Rusnak University of Rochester Innovations (30)
	Susan Keyes Northeastern University Innovations (29)
	See All People (10) »